{"id":93,"date":"2025-08-01T21:11:02","date_gmt":"2025-08-01T21:11:02","guid":{"rendered":"https:\/\/dermacab.net\/?page_id=93"},"modified":"2025-08-02T21:17:44","modified_gmt":"2025-08-02T21:17:44","slug":"donovanose-infection-a-klebsiella-granulomatis","status":"publish","type":"page","link":"https:\/\/dermacab.net\/index.php\/prise-en-charge-des-infections-sexuellement-transmissibles-ist\/infections-sexuellement-transmissibles-ist-dorigine-bacterienne\/donovanose-infection-a-klebsiella-granulomatis\/","title":{"rendered":"\ud83e\udda0 Donovanose \u2013 Infection \u00e0 Klebsiella granulomatis"},"content":{"rendered":"\n

(Granulome inguinal)<\/em><\/h2>\n\n\n\n

\ud83d\udccc Qu\u2019est-ce que la donovanose ?<\/strong><\/h3>\n\n\n\n

La donovanose, ou granulome inguinal, est une infection sexuellement transmissible (IST) bact\u00e9rienne chronique<\/strong> due \u00e0 Klebsiella granulomatis<\/em>. Elle provoque des ulc\u00e9rations cutan\u00e9es progressives<\/strong> localis\u00e9es au niveau g\u00e9nital, souvent destructrices en l\u2019absence de traitement.<\/p>\n\n\n\n

\n

Rare, mais toujours pr\u00e9sente dans certaines r\u00e9gions tropicales et subtropicales, dont des zones d\u2019Afrique subsaharienne.<\/p>\n<\/blockquote>\n\n\n\n

\n\n\n\n

\ud83d\udd2c Mode de transmission<\/strong><\/h3>\n\n\n\n
    \n
  • Par contact sexuel direct<\/strong> avec une l\u00e9sion ulc\u00e9r\u00e9e<\/li>\n\n\n\n
  • Possible transmission non sexuelle via contact cutan\u00e9 prolong\u00e9<\/li>\n\n\n\n
  • Incubation : 1 \u00e0 4 semaines, parfois plus longue<\/li>\n<\/ul>\n\n\n\n
    \n\n\n\n

    \u26a0\ufe0f Signes cliniques<\/strong><\/h3>\n\n\n\n
      \n
    • Papule indolore \u00e9voluant en ulc\u00e9ration rouge vif, granulomateuse<\/strong>, saignant facilement au contact<\/li>\n\n\n\n
    • L\u00e9sion chronique, progressive<\/strong>, pouvant devenir extensive<\/li>\n\n\n\n
    • Localisation : organes g\u00e9nitaux, p\u00e9rin\u00e9e, parfois plis inguinaux<\/li>\n\n\n\n
    • Pas d\u2019ad\u00e9nopathie inguinale suppur\u00e9e<\/strong>, contrairement au chancre mou<\/li>\n<\/ul>\n\n\n\n
      \n

      Sans traitement, les l\u00e9sions peuvent se n\u00e9croser<\/strong>, fistuliser<\/strong>, et entra\u00eener des d\u00e9formations mutilantes<\/strong>.<\/p>\n<\/blockquote>\n\n\n\n

      \n\n\n\n

      \ud83e\uddea Diagnostic<\/strong><\/h3>\n\n\n\n
        \n
      • Difficult\u00e9 diagnostique fr\u00e9quente (maladie rare)<\/li>\n\n\n\n
      • Frottis ou biopsie : mise en \u00e9vidence des corps de Donovan<\/strong> (bact\u00e9ries intracellulaires dans les macrophages)<\/li>\n\n\n\n
      • PCR disponible dans certains laboratoires sp\u00e9cialis\u00e9s<\/li>\n\n\n\n
      • Diagnostic diff\u00e9rentiel : syphilis, chancre mou, herp\u00e8s g\u00e9nital, cancer<\/li>\n<\/ul>\n\n\n\n
        \n\n\n\n

        \ud83d\udc8a Traitement<\/strong><\/h3>\n\n\n\n
          \n
        • A<\/strong>ntibiotiques<\/li>\n<\/ul>\n\n\n\n
          \n

          Le traitement est prolong\u00e9 jusqu\u2019\u00e0 cicatrisation compl\u00e8te des l\u00e9sions<\/strong>.<\/p>\n<\/blockquote>\n\n\n\n

          \n\n\n\n

          \ud83e\uddd1\ud83c\udffd\u200d\u2695\ufe0f Prise en charge au cabinet du Dr Hadi HAKIM<\/strong><\/h3>\n\n\n\n
            \n
          • Diagnostic clinique et dermoscopique si n\u00e9cessaire<\/li>\n\n\n\n
          • Traitement antibiotique sp\u00e9cifique<\/li>\n\n\n\n
          • \u00c9valuation des IST associ\u00e9es (syphilis, VIH\u2026)<\/li>\n\n\n\n
          • Suivi \u00e9volutif jusqu\u2019\u00e0 cicatrisation<\/li>\n\n\n\n
          • R\u00e9duction du risque de r\u00e9cidive<\/li>\n<\/ul>\n\n\n\n
            \n\n\n\n

            \ud83d\udcde Consultation confidentielle pour l\u00e9sions g\u00e9nitales chroniques<\/strong><\/h3>\n\n\n\n

            \ud83d\udcde +221 33 821 31 22<\/strong>
            \ud83d\udcac WhatsApp s\u00e9curis\u00e9<\/strong>
            \ud83d\udccd Cabinet de Dermatologie, IST & Laser \u2013 Dakar<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

            (Granulome inguinal) \ud83d\udccc Qu\u2019est-ce que la donovanose ? La donovanose, ou granulome inguinal, est une infection sexuellement transmissible (IST) bact\u00e9rienne chronique due \u00e0 Klebsiella granulomatis. Elle provoque des ulc\u00e9rations cutan\u00e9es progressives localis\u00e9es au niveau g\u00e9nital, souvent destructrices en l\u2019absence de traitement. Rare, mais toujours pr\u00e9sente dans certaines r\u00e9gions tropicales et subtropicales, dont des zones d\u2019Afrique […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":214,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-93","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/pages\/93","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/comments?post=93"}],"version-history":[{"count":1,"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/pages\/93\/revisions"}],"predecessor-version":[{"id":94,"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/pages\/93\/revisions\/94"}],"up":[{"embeddable":true,"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/pages\/214"}],"wp:attachment":[{"href":"https:\/\/dermacab.net\/index.php\/wp-json\/wp\/v2\/media?parent=93"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}